Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Higher Mental Functions of the Brain: Language

Higher Mental Functions of the Brain: Language

Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Limbic System Microstructure in Neonates With Antenatal Opioid Exposure.

JAMA network open·2026

Same author

Structural and functional connectivity in infancy relate to communication skills at age 2 in children born very preterm.

medRxiv : the preprint server for health sciences·2026

Same author

Prenatal Substance Exposure and Birth Weight: Findings From the HEALthy Brain and Child Development Study.

Pediatrics·2026

Same author

Antenatal Opioid Exposure and Cerebral Cortical Maturation in Newborns.

JAMA network open·2026

Same author

Development and validation of a deep learning model for liver shear stiffness regression using abdominal multiparametric MRI across multiple sites and vendors.

European radiology·2026

Same author

Developmental disinhibition gates language lateralization in childhood.

Nature communications·2026

Search research articles

Related Experiment Video

Updated: Dec 1, 2025

Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Extremely Preterm Children Demonstrate Interhemispheric Hyperconnectivity During Verb Generation: a Multimodal

Maria E Barnes-Davis^1,2,3, Stephanie L Merhar^1,2, Scott K Holland^4,5

¹Cincinnati Children's Hospital Medical Center, Perinatal Institute.

Medrxiv : the Preprint Server for Health Sciences

|November 11, 2020

Summary

This summary is machine-generated.

Children born extremely preterm (EPT) show altered brain connectivity. This interhemispheric hyperconnectivity in EPT children is linked to better expressive language skills, potentially indicating resilience.

More Related Videos

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

Related Experiment Videos

Last Updated: Dec 1, 2025

Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

Area of Science:

Neuroscience
Developmental Psychology
Pediatrics

Background:

Children born extremely preterm (EPT) face developmental challenges, particularly in language acquisition.
Understanding the neural basis of language in EPT children is crucial for early intervention.

Approach:

Utilized fMRI-constrained magnetoencephalography (MEG) in 73 children (4-6 years old), comparing EPT and term-born (TC) groups.
Assessed language network extent and functional connectivity (Phase Locking Value, PLV) during a verb generation task.
Employed Network Based Statistics (NBS) to analyze connectivity differences in beta and gamma frequency bands.

Key Points:

No significant differences in fMRI language representation between EPT and TC groups.
MEG revealed significant group differences in functional connectivity.
EPT children exhibited hyperconnectivity in a specific subnetwork within beta and gamma bands.
Gamma band subnetwork strength positively correlated with expressive language scores in EPT children.

Conclusions:

Interhemispheric hyperconnectivity may serve as a neural marker for language resilience in extremely preterm children.
This finding offers insights into brain plasticity and compensatory mechanisms following preterm birth.
Further research can explore therapeutic targets for enhancing language development in this vulnerable population.