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Updated: Dec 1, 2025
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Clinicopathological analysis of acral melanoma in a single center: a study of 45 cases
Bruno de Castro E Souza1, Diego Henrique Morais Silva2, Denis Miyashiro3
1Médico Dermatologista - Departamento de Dermatologia do Hospital das Clínicas da Universidade de São Paulo, São Paulo, SP, Brasil.
Objective:
The relationship between the clinicopathological and sociodemographics characteristics of acral melanomas diagnosed at the Hospital do Servidor Público Estadual de São Paulo was analyzed and traced between 1997 and 2016.
Methods:
An observational, descriptive, and retrospective study of patients diagnosed with acral melanoma was performed at Hospital do Servidor Público Estadual de São Paulo. Sociodemographic and clinicopathological characteristics were collected and analyzed.
Results:
Forty-five patients with acral melanomas were found during the evaluation period. Thirty-one were females, and 14 were males (68.89% and 31.3%, respectively). Most of the cases were invasive (88.37%), and the predominant histological subtype was the acral lentiginous (91.11%). The plantar region was the most prevalent (64.44%). The median Breslow index was 3 mm, and there was a tendency towards greater severity in male patients.
Conclusions:
Acral site melanomas are detected diagnosed when they reach more advanced stages, which leads to a worse prognosis for patients. Late detection assumes even greater importance in highly mixed and black populations, such as the Brazilian population.
