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Updated: Dec 1, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Frailty and associated risk factors in patients with chronic kidney disease on dialysis
Gabriela Dutra Gesualdo1, Juliana Gomes Duarte2, Marisa Silvana Zazzetta2
1Escola de Enfermagem de Ribeirão Preto, Universidade de São Paulo (USP). Rodovia Washington Luís, km 235, SP-310. 13565-905 São Carlos SP Brasil. fabi_ferreira@yahoo.com.br.
Abstract:
The objective of this article is to determine the relationship between frailty and socio-demographic/clinical characteristics in patients with chronic kidney disease on dialysis. A cross-sectional study was conducted with 107 participants. Descriptive, correlation and logistic regression analyses were performed, with the level of significance set to 5% (p < 0.05). The prevalence of frailty was 47.66%. Frailty was negatively correlated with cognition (r = -0.30; p = 0.002), functioning on instrumental activities of daily living (r = -0.41; p = 0.000) and hematocrit level (r = -0.19; p = 0.04). The proportion of frailty increased with the age of the participants (OR = 1.03; 95%CI: 1.004-1.069; p = 0.02). Individuals with chronic kidney disease on dialysis had high percentages of frailty, which was associated with an older age and correlated with cognition, functioning on instrumental activities of daily living and a lower hemotocrit level.
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