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Chronic total occlusion percutaneous coronary intervention: managing perforation complications
Francesco Moroni1, Emmanouil S Brilakis2, Lorenzo Azzalini3
1Università Vita-Salute San Raffaele , Milan, Italy.
Insights
Coronary artery perforation (CAP) is a rare but serious complication of percutaneous coronary intervention (PCI), especially in chronic total occlusion (CTO) PCI. Prompt management with available devices and training is crucial for optimal outcomes.
Area of Science:
- Interventional Cardiology
- Cardiovascular Imaging
- Medical Device Technology
Background:
- Coronary artery perforation (CAP) is an infrequent complication of percutaneous coronary intervention (PCI), with higher incidence during complex chronic total occlusion (CTO) PCI.
- CAP can lead to severe consequences such as cardiac tamponade and death.
- The complexity of CTO lesions and recanalization techniques increases the risk of CAP.
Purpose of the Study:
- To review features of CTO PCI predisposing to CAP.
- To describe procedural scenarios where CAP may occur.
- To present a universal management algorithm and treatment options for CAP.
Main Methods:
- Expert review of current literature and clinical practices.
- Discussion of predisposing factors and procedural scenarios for CAP in CTO PCI.
- Detailed presentation of CAP treatment devices, techniques, and imaging support.
Main Results:
- CAP incidence is higher in CTO PCI due to lesion complexity and advanced techniques.
- A universal management algorithm for CAP is proposed.
- Available devices and techniques for CAP treatment, including imaging and medical/surgical management, are discussed.
Conclusions:
- The incidence of CAP is expected to rise with increasing CTO PCI volumes and complexity.
- Adherence to best practices, availability of specialized equipment, and adequate training are essential for CAP prevention and management.
- Effective management strategies involve sealing CAP, pericardiocentesis, hemodynamic support, and comprehensive training.
Introduction:
Coronary artery perforation (CAP) is an infrequent (<1%) complication of percutaneous coronary intervention (PCI), that can lead to dramatic consequences, including tamponade and death. The incidence of CAP is higher (4-9%) in chronic total occlusion (CTO) PCI due higher complexity of these lesions and the techniques used to recanalized them.
Areas Covered:
In this Expert Review, we discuss the specific features of CTO PCI predisposing to CAP. We also describe the typical procedural scenarios in which CAP can occur and provide a universal management algorithm. Currently available devices and techniques for CAP treatment are presented in detail. Finally, we discuss imaging support for diagnosis of pericardial effusion in CAP as well as medical and surgical management.
Expert Opinion:
With increasing volumes and complexity of CTO PCI, the incidence of CAP is likely to rise. Adherence to good catheterization laboratory practices, availability of dedicated equipment to seal CAP, perform pericardiocentesis, and provide hemodynamic support, as well as adequate training, are pillars for the prevention and optimal management of CAP during CTO PCI.
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