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Related Experiment Videos

Mycoses caused by Candida lusitaniae.

T L Hadfield1, M B Smith, R E Winn

  • 1Department of Pathology, Wilford Hall United States Air Force Medical Center, Lackland Air Force Base, Texas 78236-5300.

Reviews of Infectious Diseases
|September 1, 1987
PubMed
Summary

Candida lusitaniae is an opportunistic fungal pathogen causing infections in immunocompromised individuals. This yeast exhibits resistance to amphotericin B, posing treatment challenges and requiring careful identification.

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Area of Science:

  • Mycology
  • Infectious Diseases
  • Clinical Microbiology

Background:

  • Candida lusitaniae is a yeast with low infection rates in immunocompetent individuals.
  • It is increasingly recognized as an opportunistic pathogen in immunocompromised hosts.

Observation:

  • This fungus often shows resistance to amphotericin B, complicating treatment strategies.
  • C. lusitaniae can be misidentified as other common yeasts like Candida tropicalis or Saccharomyces cerevisiae.

Findings:

  • In vitro studies indicate achievable minimal inhibitory concentrations for some antifungals, but not fungicidal levels.
  • Antifungal susceptibility testing is crucial for guiding therapy against C. lusitaniae.

Implications:

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  • Accurate identification and consideration of C. lusitaniae are vital when detected in clinical specimens.
  • This emerging pathogen necessitates awareness in clinical settings for effective management of invasive fungal infections.