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A call for a streamlined ethics review process for multijurisdictional, child health research studies

Brigitte Lemyre1,2, Jaya P Bodani3,4, Stefani Doucette5

  • 1Division of Neonatology, Children's Hospital of Eastern Ontario, Ottawa.

Paediatrics & Child Health
|November 12, 2020
PubMed

Insights

Conducting multi-site neonatal research in Canada faces significant ethics review hurdles. Streamlining these processes is crucial for timely, valid, and generalizable clinical research for infants.

Area of Science:

  • Neonatal research
  • Clinical trials
  • Pediatric health

Background:

  • Multi-jurisdictional research is essential for robust neonatal studies.
  • Current ethics review processes in Canada create substantial delays and costs.
  • These challenges can impede or halt critical research projects.

Purpose of the Study:

  • To describe the experience of obtaining ethics review for a multi-site neonatal study across 7 Canadian provinces.
  • To highlight the challenges encountered in multijurisdictional research ethics review.
  • To advocate for practical solutions to improve research efficiency.

Main Methods:

  • A single research project comparing two standard therapies for preterm infants with respiratory distress syndrome sought ethics approval.
  • The study involved 13 sites across 7 Canadian provinces.
  • The process of navigating multijurisdictional ethics review was documented.

Main Results:

  • The study encountered significant hurdles in the ethics review process.
  • Delays and administrative costs were incurred.
  • The experience underscores the need for streamlined review procedures.

Conclusions:

  • Multijurisdictional ethics review in Canada presents significant barriers to neonatal research.
  • Collaborative efforts are needed to identify practical solutions.
  • Improving the ethics review process will benefit researchers, ethics boards, and Canadian children and families.

Keywords:
Multicenter researchneonatologyresearch ethics review

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