Related Experiment Video
Updated: Nov 30, 2025
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Closing gigantic left atrial appendage using a LAmbre Closure System: First implant experience in North America
Taku Inohara1, Michael Y Tsang1, Christopher Lee1
1Division of Cardiology, Vancouver General Hospital, Vancouver, British Columbia, Canada.
Introduction:
Despite maturing experience and growing procedural familiarity, there remain challenges in percutaneous left atrial appendage (LAA) closure due to anatomical complexities.
Methods:
We report a complex and extremely large LAA that was successfully closed percutaneously using a LAmbre Closure System (Lifetech Scientific Corp.). Cardiac computed tomography angiography demonstrated a gigantic multilobed LAA measuring 48 × 45.3 mm at the level of the ostium that cannot be occluded by the currently approved LAA closure devices in Canada.
Results:
The manufacturer custom-made a LAmbre 30/50 mm (lobe/disc) device to fit this patient's LAA according to his CTA, which was successfully deployed under fluoroscopy and transesophageal echocardiogram guidance without procedure-related complications.
Conclusion:
The LAmbre device may be considered to close very large LAAs.
