Vitreous hemorrhage secondary to age-related macular degeneration

The clinical features of two patients with vitreous hemorrhage secondary to age-related macular degeneration and the histopathological findings in one of these cases are reported. Twenty additional cases are reviewed and compared with previously reported series. In patients with vitreous hemorrhage secondary to age-related macular degeneration, the appearance of vitreal blood is often preceded by extensive subretinal hemorrhage. Although this condition may be confused with a vitreous hemorrhage accompanying choroidal malignant melanoma, the correct diagnosis is usually apparent from clinical findings and ultrasonography. In most patients the prognosis for visual improvement is poor because of macular degeneration and extensive subretinal hemorrhage. A vitrectomy to remove the vitreous hemorrhage associated with macular degeneration is rarely beneficial.