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Gastritis: update on etiological features and histological practical approach
Gianmaria Pennelli1, Federica Grillo2,3, Francesca Galuppini1
1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Pathologica
|November 12, 2020
Summary
Gastric pathology is shifting, with fewer H. pylori cases and more drug-induced lesions in cancer patients. This review covers key gastric biopsy findings and current expert guidelines.
Area of Science:
- Gastroenterology and Pathology
- Oncology
- Drug-induced Lesions
Background:
- Gastric biopsies are common in pathology practice.
- Western countries see declining H. pylori-related pathologies.
- Iatrogenic lesions from new cancer drugs are increasing.
Purpose of the Study:
- To describe elementary lesions in gastric biopsies.
- To review recent recommendations and guidelines.
- To address the changing landscape of gastric pathology.
Main Methods:
- Literature review of recent publications.
- Analysis of expert opinions and guidelines.
- Focus on elementary lesion descriptions.
Main Results:
- Significant decline in H. pylori-related gastric pathologies observed.
- Expansion of iatrogenic lesions due to novel oncological drugs noted.
- Elementary lesions in gastric biopsies are detailed.
Conclusions:
- Gastric pathology is evolving due to reduced H. pylori and increased drug-induced changes.
- Current guidelines and expert opinions are crucial for diagnosis.
- Understanding these shifts is vital for pathologists.
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