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Failure of high dose mebendazole as a microfilaricide in patients with loiasis
1Laboratoire de Recherches, Albert Schweitzer Hospital, Lambarene, Gabon.
Abstract:
The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied. The drug regimen was 1 g twice daily for 21 days in adults. During and after treatment, the microfilarial density was unchanged. Therefore, mebendazole has no direct effect on the microfilarial density of Loa loa.