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Updated: Nov 30, 2025

Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis
Published on: June 24, 2018
Biomineralization at fluid interfaces
Manuel Cano1, Juan J Giner-Casares1
1Departamento de Química Física, Instituto Universitario de Investigación en Química Fina y Nanoquímica IUNAN, Facultad de Ciencias, Universidad de Córdoba (UCO), Campus de Rabanales, Ed. Marie Curie, E-14071 Córdoba, Spain.
Abstract:
Biomineralization is of paramount importance for life on Earth. The delicate balance of physicochemical interactions at the interface between organic and inorganic matter during all stages of biomineralization resembles an extremely high complexity. The coordination of this sophisticated biological machinery and physicochemical scenarios is certainly a wonderful show of nature. Understanding of the biomineralization processes is still far from complete. The recent advances in biomineralization research from the Colloid and Interface Science perspective are reviewed herein. The synergy between this two fields of research is demonstrated. The unique opportunities offered by purposefully designed fluid interfaces, mainly Langmuir monolayers are presented. Biomedical applications of biomineral-based nanostructures are discussed, showing their improved biocompatibility and on-demand delivery features. A brief guide to the array of state-of-the-art experimental techniques for unraveling the mechanisms of biomineralization using fluid interfaces is included. In summary, the fruitful and exciting crossroad between Colloid and Interface Science with Biomineralization is exhibited.
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