Low concentration noroxin detection using terahertz spectroscopy combined with metamaterial

Area of Science:

• Food Safety
• Analytical Chemistry
• Materials Science

Background:

• Antibiotic residues in poultry products pose risks to food safety and human health.
• Accurate and rapid detection methods for antibiotic drug content are crucial.

Purpose of the Study:

• To develop and test a novel metamaterial-based terahertz (THz) spectroscopy method for detecting low concentrations of the quinolone antibiotic noroxin.
• To establish a theoretical and experimental basis for rapid detection of quinolone antibiotic residues in food.

Main Methods:

• Designed and experimentally verified a new metamaterial structure using computational electromagnetics.
• Simulated and measured transmission spectra of metamaterials with varying photoresist thicknesses and noroxin concentrations.
• Prepared test samples from a standard noroxin solution and performed multivariate data analysis.

Main Results:

• The metamaterial structure was successfully designed and verified.
• Transmission spectra correlated with noroxin concentration were observed.
• The developed method achieved a detection limit of 0.01 µg/mL for noroxin.

Conclusions:

• The novel metamaterial-based THz spectroscopy method effectively detects low concentrations of noroxin.
• This technique provides a viable approach for the rapid detection of quinolone antibiotic residues in food matrices.
• The study lays the groundwork for improved food safety monitoring.