Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Psychosis: Goals of Pharmacotherapy

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

Treatment Strategies for Psychological Disorders

Treatment Strategies for Psychological Disorders

Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...

Operant Conditioning Intervention

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...

Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patient-derived tumoroids recapitulate the morphologic and molecular features of pediatric brain tumors.

NPJ precision oncology·2025

Same author

Leveraging knowledge for explainable AI in personalized cancer treatment: challenges and future directions.

Frontiers in digital health·2025

Same author

The phenomenology within Cézanne's work: a reflection - Psychiatry in art.

The British journal of psychiatry : the journal of mental science·2024

Same author

Palinacousis in amyloidosis: exploring the hallucinatory phenomenon in brain pathology-a case report.

Journal of medical case reports·2024

Same author

Cariprazine in the acute treatment of unipolar and bipolar depression: A systematic review and meta-analysis.

Journal of affective disorders·2024

Same author

The Immunopeptidomics Ontology (ImPO).

Database : the journal of biological databases and curation·2024

Search research articles

Related Experiment Video

Updated: Jul 2, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Electroconvulsive Therapy in Refractory Obsessive-Compulsive Disorder: A Case Report.

João Martins-Correia¹, Nuno Rodrigues-Silva, Susana Nunes¹

¹From the Department of Psychiatry and Mental Health, Local Health Unit of Guarda, Guarda.

The Journal of ECT

|November 12, 2020

Summary

Electroconvulsive therapy (ECT) shows promise for severe obsessive-compulsive disorder (OCD). This case report highlights a patient with refractory OCD who experienced significant improvement with ECT, suggesting its potential utility.

More Related Videos

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Published on: April 11, 2019

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Related Experiment Videos

Last Updated: Jul 2, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

Published on: April 11, 2019

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Area of Science:

Neuroscience
Psychiatry

Background:

Electroconvulsive therapy (ECT) is a highly effective treatment for severe psychiatric conditions.
Despite its efficacy, ECT is underutilized due to significant public stigma.
Obsessive-compulsive disorder (OCD) is not typically considered a primary indication for ECT.

Observation:

The authors present a case of a patient with treatment-resistant OCD.
This patient received ECT as a therapeutic intervention.
A remarkable clinical response and functional improvement were observed post-ECT.

Findings:

The case demonstrates a positive response to ECT in a patient with refractory OCD.
This adds to a small but growing body of literature suggesting ECT's potential in OCD treatment.
The response observed was clinically significant and led to functional gains.

Implications:

Identifying predictors of ECT response in OCD is crucial for clinical guidance.
ECT may be a viable option for carefully selected patients with refractory OCD.
Further research is warranted to explore ECT's role and optimize its application in OCD management.