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Published on: April 12, 2021
Electrolyte disorders in stable renal allograft recipients
Georg Beilhack1, Gregor Lindner2, Georg-Christian Funk3
1Department of Nephrology and Dialysis, Medical University Vienna, Austria.
Electrolyte and acid-base disorders are common in stable kidney transplant recipients, affecting 64% of patients. These imbalances are typically mild and influenced by kidney function and medications.
Area of Science:
- Nephrology
- Transplantation Medicine
- Clinical Chemistry
Background:
- Electrolyte and acid-base disorders are common post-renal transplant.
- Limited data exists on long-term stable allograft function.
- Prevalence and contributing factors in stable patients are not well-defined.
Purpose of the Study:
- To determine the prevalence of electrolyte and acid-base disorders.
- To identify patterns and risk factors in stable renal allograft recipients.
- To analyze contributing factors like renal function and medications.
Main Methods:
- Cross-sectional study design.
- Analysis of 576 renal transplant recipients with stable graft function (serum creatinine <2.0 mg/dl).
- Multivariate logistic regression to identify risk factors.
Main Results:
- 64% of patients (n=576) had at least one disorder.
- Most common: hypomagnesemia (25%), hyperkalemia (12.8%), hypercalcemia (12%).
- Renal function and concomitant medications were significant contributing factors.
Conclusions:
- Electrolyte and acid-base disorders are frequent in stable renal allograft recipients.
- Disorders are generally mild.
- Multiple electrolyte abnormalities can co-occur without a predictable pattern.
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