Related Experiment Video
Updated: Nov 30, 2025

11:50
EEG Mu Rhythm in Typical and Atypical Development
Published on: April 9, 2014
26.3K
Electroencephalography Attenuations in Adults: Clinical Correlates
1Division of Neurology, College of Medicine, University of Saskatchewan, Saskatoon, SaskatchewanCanada.
Summary
Spontaneous intermittent generalized attenuations (SIGAs) on electroencephalography (EEG) are linked to poor clinical outcomes. Over half of patients with SIGAs experienced mortality or intensive care unit admission.
Area of Science:
- Neurology
- Clinical Neurophysiology
Background:
- Spontaneous intermittent generalized attenuations (SIGAs) are transient decreases in electroencephalography (EEG) amplitude.
- SIGAs can occur due to physiological processes, external stimuli, or pathological conditions.
Purpose of the Study:
- To investigate the relationship between SIGAs and clinical outcomes in patients.
Main Methods:
- Retrospective review of demographic, clinical, and modified Rankin Scale (mRS) data.
- Analysis of EEG recordings from 22 consecutive patients diagnosed with SIGAs.
Main Results:
- 54.5% of patients (12/22) with SIGAs died during the study period.
- 54.5% of patients (12/22) with SIGAs required admission to an intensive care unit or coronary care unit.
Conclusions:
- SIGAs on EEG may indicate a poor prognosis.
- Further prospective studies comparing patients with and without SIGAs are warranted to confirm these findings.

