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Three new phenanthrenes from Pholidota chinensis Lindl. and their antibacterial activity
Huihui Ti1, Zixi Zhuang2, Yan Li3,4
1School of Clinical Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
Abstract:
Three new phenanthrenes were isolated from Pholidota chinensis Lindl. Their structures were elucidated on the basis of spectroscopic techniques and comparison of their data to the values reported in the literature. From the 95% EtOH extract, three new compounds, namely 9, 10-dihydro-2, 4, 6-trihydroxy-7-methoxyphenanthrene (1), 11-methoxyflaccidin (2), and 2-methoxy-3,7-dihydroxy-5H phenanthro[4,5-bcd] pyran (3), were identified. Compound 3 showed an MIC50 of 68.39 µM against Staphylococcus aureus subsp. Aureus.
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