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Updated: Nov 30, 2025

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
[Minimally invasive methods of treatment of interstitial cystitis/painful bladder syndrome]
A G Martov1,2, N G Muzhetskaya1, Y R Slyukova3
1Department of urology and Andrology of Federal Medical and Biological Center named after A.I. Burnazyan FMBA, Moscow, Russia.
Abstract:
Interstitial Cystitis (IC) or Painful Bladder Syndrome (PBS) is a heterogeneous disease which pathogenetic mode development is not fully studied. In the presented literature review IC/PBS is considered as urothelial dysfunction. The main issues discussed relate to IC/PBS diagnosis and minimally invasive methods of its treatment including intravesical instillations of therapeutic agents, botulinum toxin injections into bladder wall and hydrodistension. Efficacy of the above therapeutic methods is far from the desired what gives rise to search novel minimally invasive technologies and protocols to improve the outcomes of traditional treatment methods.
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