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Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Advancing Biosensors with Machine Learning.

Feiyun Cui1, Yun Yue2, Yi Zhang3

  • 1Department of Chemical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachusetts 01609, United States.

ACS Sensors
|November 13, 2020
PubMed
Summary
This summary is machine-generated.

Machine learning (ML) enhances biosensor capabilities for detection and diagnosis. This review explores advanced ML methods, including deep learning, to improve biosensor performance and data analysis.

Keywords:
CNNSERSartificial intelligence (AI)chemometricsdeep learningintelligent biosensormachine learning (ML)multidimensional featuressensing datawearable electronics

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Area of Science:

  • Biomedical Engineering
  • Data Science
  • Analytical Chemistry

Background:

  • Chemometrics are vital for biosensor applications in detection, analysis, and diagnosis.
  • Machine learning (ML), a subset of artificial intelligence (AI), has seen significant advancements.
  • Advanced ML methods, particularly deep learning, are underutilized in the biosensor field.

Purpose of the Study:

  • To systematically review the benefits of ML in biosensor technology.
  • To summarize the pros and cons of common ML algorithms for biosensor data.
  • To highlight the potential of deep learning (CNN, RNN) for biosensor development.

Main Methods:

  • Discussion of ML algorithms applied to biosensor data analysis.
  • Review of diverse biosensor types enhanced by ML (electrochemical, wearable, spectral, fluorescence, colorimetric).
  • Introduction to ML in biosensor networks and data fusion.

Main Results:

  • ML offers significant advantages for biosensor data analysis and interpretation.
  • Deep learning methods like CNN and RNN show particular promise for complex biosensor data.
  • ML integration expands the scope of biosensor applications in detection, analysis, and diagnosis.

Conclusions:

  • ML, especially deep learning, can substantially advance biosensor performance.
  • This review bridges the gap between ML and biosensors, expanding chemometric possibilities.
  • The integration of ML promises improved detection, analysis, and diagnostic capabilities through biosensors.