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Isolated Oculomotor Nerve Palsy - A Rare Initial Manifestation of Tuberculous Meningitis
Akhilesh Kumar Singh1, Prabhat Agarwal2, Rohit Baiswar3
1Assistant Professor, Sarojini Naidu Medical College, Agra, Uttar Pradesh.
Abstract:
Tuberculous meningitis (TBM) is a sub-acute / chronic meningitis known for its diverse manifestations which may lead to delayed diagnosis. An isolated oculomotor nerve palsy as an initial presentation of TB meningitis is quite rare. One such case has presented here; A 18 year female presented to us with ptosis of the left eye. Complete neurological examination revealed it to be a case of isolated 3rd cranial nerve palsy. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) brain revealed no significant abnormality. Cerebrospinal fluid (CSF) analysis was done and diagnosis of Tuberculous Meningitis was confirmed. This case report focuses on the fact that tuberculous meningitis should be included in the differential diagnosis of isolated oculomotor nerve palsy.
Insights
Tuberculous meningitis (TBM) can present rarely as isolated oculomotor nerve palsy. Early diagnosis is crucial, and TBM should be considered in such neurological presentations.
Area of Science:
- Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Tuberculous meningitis (TBM) is a severe form of meningitis with varied clinical presentations.
- Delayed diagnosis of TBM can lead to significant neurological deficits.
Observation:
- An 18-year-old female presented with isolated left-sided ptosis.
- Neurological examination confirmed an isolated 3rd cranial nerve palsy.
- Brain imaging (CT and MRI) showed no abnormalities.
Findings:
- Cerebrospinal fluid (CSF) analysis confirmed the diagnosis of Tuberculous Meningitis.
- This case highlights an unusual initial manifestation of TBM.
Implications:
- Tuberculous meningitis should be included in the differential diagnosis for isolated oculomotor nerve palsy.
- Raising awareness of rare TBM presentations can improve diagnostic timelines.
- Early recognition and treatment of TBM are vital for patient outcomes.
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