Isolated Oculomotor Nerve Palsy - A Rare Initial Manifestation of Tuberculous Meningitis

Akhilesh Kumar Singh1, Prabhat Agarwal2, Rohit Baiswar3

  • 1Assistant Professor, Sarojini Naidu Medical College, Agra, Uttar Pradesh.

Insights

Tuberculous meningitis (TBM) can present rarely as isolated oculomotor nerve palsy. Early diagnosis is crucial, and TBM should be considered in such neurological presentations.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Tuberculous meningitis (TBM) is a severe form of meningitis with varied clinical presentations.
  • Delayed diagnosis of TBM can lead to significant neurological deficits.

Observation:

  • An 18-year-old female presented with isolated left-sided ptosis.
  • Neurological examination confirmed an isolated 3rd cranial nerve palsy.
  • Brain imaging (CT and MRI) showed no abnormalities.

Findings:

  • Cerebrospinal fluid (CSF) analysis confirmed the diagnosis of Tuberculous Meningitis.
  • This case highlights an unusual initial manifestation of TBM.

Implications:

  • Tuberculous meningitis should be included in the differential diagnosis for isolated oculomotor nerve palsy.
  • Raising awareness of rare TBM presentations can improve diagnostic timelines.
  • Early recognition and treatment of TBM are vital for patient outcomes.

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