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"Ossifying" mucoepidermoid carcinoma: A deceptive clinical presentation
Brian Wolf1, Stephen Roth2, John Fantasia3
1Oral and Maxillofacial Surgery Resident, Nassau University Medical Center, East Meadow, NY, USA.
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
|November 14, 2020
Summary
Mucoepidermoid carcinoma, a common salivary gland cancer, can rarely present with intratumoral bone. This unusual finding, seen in a floor of mouth mass, does not appear to affect prognosis but aids in diagnosis.
Area of Science:
- Oncology
- Pathology
Background:
- Mucoepidermoid carcinoma is the most common malignant salivary gland tumor, comprising 27% of all cases.
- It exhibits diverse histology with described morphologic variants.
Observation:
- A rare instance of intratumoral bone formation within mucoepidermoid carcinoma is presented.
- The case involved a 48-year-old Hispanic woman with a floor of mouth swelling.
Findings:
- Computed tomography revealed a soft tissue mass with intralesional radiopacities, indicating bone formation.
- The etiology of this intratumoral bone is currently unknown.
- This calcification is believed to be independent of the overall disease prognosis.
Implications:
- Awareness of this rare feature is crucial for clinicians to prevent misdiagnosis.
- Recognizing intratumoral bone in mucoepidermoid carcinoma can expedite appropriate treatment.
- This case highlights the importance of detailed histopathological analysis in salivary gland malignancies.
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