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Updated: Aug 2, 2026

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
Published on: November 16, 2011
[Modulation of the hypoglycemic effect of insulin during lateral transcerebral electrostimulation]
Abstract:
Experiments on rabbits have studied the effect of lateral transcerebral electrical modulations with weak impulse current on hypoglycemic insulin effect. Two series of experiments were performed on 15 intact animals each. Right-sided electrical stimulation in the first series of experiments produced a trend toward a decrease in fasting blood sugar concentration. In the second series of experiments there was hypoglycemic action of a standard exogenous insulin dose. Transcerebral left-sided electrical stimulation caused no such effects. It has been concluded that the modulation of hypoglycemic exogenous insulin effect was possible due to unilateral transcerebral right-sided electrical stimulation.

