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Published on: March 8, 2024
Exploring the multifocal therapeutic approaches in COVID-19: A ray of hope
Arun Kumar1, Asmita Deka Dey1, Tapan Behl1
1Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Abstract:
The ongoing global pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is marked as one of the most challenging infectious diseases in the history of mankind with affliction of ~29,737,453 confirmed cases globally. Looking at the present scenario where there is a parallel increment in curve with time, there is an utmost emergency to discover a perennial solution to this life-threatening virus which has led the Human race in an unusual state of affair. The entire health care fraternity is engaged in endeavouring an ultimate way out to hit this pandemic but no such research made till now has been approved yet, to have the potential to bring an end to this fatal situation. Although a few possible treatment choices exist at the moment yet the requirement to search for a still better therapeutic option remains persistent. Global laboratories are working day and night in search for an effective vaccine, many are undergoing clinical trials but their commercialization is no less than a year away. The present review highlights the current potential therapies viz., vaccines, immunotherapies, convulsant plasma therapies, corticosteroids, antithrombotic, intravenous immunoglobulins, nocturnal oxygen therapy etc. that may prove beneficial in attenuating the pandemic situation. However, comparison and presentation of collective data on the therapeutic advancements in mitigating the pandemic situation needs further clinical investigations in order to prove boon to mankind.
Insights
The COVID-19 pandemic requires urgent solutions. This review examines current therapies like vaccines and immunotherapies, highlighting the need for further clinical investigation into their effectiveness against SARS-CoV-2.
Area of Science:
- Infectious Diseases
- Virology
- Public Health
Background:
- The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic presents a significant global health challenge.
- Over 29 million cases have been confirmed worldwide, necessitating urgent therapeutic solutions.
Purpose of the Study:
- To review and highlight potential therapies for mitigating the COVID-19 pandemic.
- To assess the current landscape of SARS-CoV-2 treatments and vaccines.
Main Methods:
- Literature review of current therapeutic advancements.
- Analysis of potential treatments including vaccines, immunotherapies, and supportive care.
Main Results:
- Several potential therapies are under investigation, including vaccines, immunotherapies, convalescent plasma, corticosteroids, and others.
- Vaccine development is ongoing, with many candidates in clinical trials, but widespread availability is estimated to be a year away.
Conclusions:
- While existing treatments offer some benefit, the search for more effective options continues.
- Further clinical investigations are required to validate the efficacy of reviewed therapies in combating the SARS-CoV-2 pandemic.
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