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Oral ciprofloxacin as prophylaxis for optical urethrotomy
1Department of Medical Microbiology, London Hospital.
British Journal of Urology
|October 1, 1987
Summary
Antibiotic prophylaxis may prevent post-operative bacteriuria in patients undergoing optical urethrotomy for urethral strictures. Ciprofloxacin prophylaxis resulted in sterile urine in all treated patients, suggesting its potential benefit.
Area of Science:
- Urology
- Infectious Disease
Background:
- Urethral strictures are known to increase the risk of bacteriuria.
- The necessity of antibiotic prophylaxis during optical urethrotomy is not well-established.
Purpose of the Study:
- To evaluate the efficacy of antibiotic prophylaxis in preventing post-operative bacteriuria following optical urethrotomy.
Main Methods:
- A randomized study involving 23 patients undergoing optical urethrotomy.
- Patients received either no antibiotic prophylaxis or a short course of oral ciprofloxacin.
- Urine cultures were assessed pre- and post-operatively.
Main Results:
- Four patients (two with sterile pre-operative urine, two with pre-operative bacteriuria) who received no prophylaxis developed post-operative bacteriuria.
- All patients who received ciprofloxacin prophylaxis maintained sterile urine post-operatively.
Conclusions:
- Antibiotic prophylaxis, specifically with ciprofloxacin, appears effective in preventing post-operative bacteriuria after optical urethrotomy.
- Prophylactic antibiotics may be indicated for patients undergoing this procedure.
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