Thoracic duct stent-graft decompression with 3-month patency: Revisiting a historical treatment option for portal hypertension
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H McGregor1, G Woodhead1, M Patel1
1Department of Medical Imaging, University of Arizona, Tucson, Arizona USA.
Insights
Thoracic duct stent-graft decompression effectively treated variceal hemorrhage in a cirrhosis patient. This minimally invasive approach shows promise for managing portal hypertension complications.
Area of Science:
- Interventional Radiology
- Hepatology
- Vascular Surgery
Background:
- Portal hypertension in cirrhosis leads to elevated thoracic duct flow and pressure.
- Traditional treatments for portal hypertension complications include thoracic duct drainage and lymphovenous bypass.
- Minimally invasive techniques are sought for managing complex cirrhotic complications.
Observation:
- A patient with cirrhosis, portal hypertension, and variceal hemorrhage underwent thoracic duct stent-graft placement.
- The procedure aimed to decompress the thoracic duct across the lymphovenous junction.
- Initial venography showed partial stent-graft patency with fibrin sheath formation.
Findings:
- Percutaneous thoracic duct stent-graft placement successfully resolved acute variceal hemorrhage.
- Endoscopy confirmed decompression of bleeding varices post-procedure.
- Stent-graft revision achieved full patency at 3-month follow-up, preventing recurrent hemorrhage.
Implications:
- Thoracic duct stent-graft decompression offers a potential minimally invasive treatment for cirrhotic portal hypertension.
- This technique may provide an alternative to traditional surgical interventions for variceal bleeding.
- Further research is warranted to establish the long-term efficacy and safety of this approach.
Abstract:
This report introduces the rationale for thoracic duct stent-graft decompression in cirrhotic patients with portal hypertension and provides a case example with 3-month stentgraft patency. Thoracic duct flow and pressure are elevated in cirrhosis. Historically, complications of portal hypertension have been successfully treated with external drainage of the thoracic duct or surgical lymphovenous bypass. A 45-year-old woman with cirrhosis, chronic portosplenomesenteric thrombosis, and acute variceal hemorrhage underwent percutaneous thoracic duct stent-graft placement across the lymphovenous junction. The hemorrhage subsequently resolved and follow up endoscopy demonstrated decompression of the bleeding varices. Venography 40 days later demonstrated a partially patent stent-graft with fibrin sheath formation distally. The stent-graft was extended distally to the right atrium and was fully patent on venography 3 months later. The patient had no further episodes of hemorrhage.
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