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Hot Biological Catalysis: Isothermal Titration Calorimetry to Characterize Enzymatic Reactions
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Simultaneous determination of thermodynamic and kinetic data by isothermal titration calorimetry

Steffen Glöckner1, Gerhard Klebe1

  • 1Philipps-University Marburg, Institute for Pharmaceutical Chemistry, Marbacher Weg 6, 35037 Marburg, Germany.

Biochimica Et Biophysica Acta. General Subjects
|November 16, 2020
PubMed
Abstract

Keywords:
1:1 protein-ligand complexesDrug optimizationKinetic binding dataMeasurement protocolThermodynamic binding datakinITC

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