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Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Such genes that act...
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Multidisciplinary consensus on cancer management during pregnancy.

A Cubillo1, S Morales2, E Goñi3

  • 1Department of Medical Oncology, Centro Integral Oncológico Clara Campal, Hospital Universitario HM Sanchinarro, Sociedad Española de Oncología Médica (SEOM), Madrid, Spain. acubillo@hmhospitales.com.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|November 16, 2020
PubMed
Summary

Managing cancer during pregnancy requires multidisciplinary collaboration. Consensus recommendations harmonize care for pregnant patients and their fetuses, optimizing outcomes.

Keywords:
Antineoplastic agentsChild developmentDiagnosisFollow-upPrenatal careRadiotherapySurgerySystemic therapies

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Area of Science:

  • Oncology
  • Obstetrics
  • Radiology

Background:

  • Cancer in pregnancy presents complex diagnostic, prognostic, and therapeutic challenges.
  • Management requires integrated medical action for both the pregnant patient and the developing fetus.
  • Gestational period significantly influences proposed treatment protocols and their limitations.

Framework:

  • Consensus recommendations developed by a multidisciplinary expert group from major Spanish scientific societies.
  • Harmonization of management strategies for pregnant cancer patients.
  • Optimization of healthcare through collaborative decision-making.

Implementation:

  • Consideration of gestational week at diagnosis and tumor characteristics is crucial.
  • Strong recommendation for multidisciplinary team assessment and guidance throughout the patient's journey.
  • Involvement of specialized obstetricians in fetal monitoring and management within a cancer committee.

Implications:

  • Improved and standardized care for pregnant women diagnosed with cancer.
  • Enhanced collaboration among medical specialists for better patient and fetal outcomes.
  • Establishment of best practices for managing complex pregnancy-related cancer cases.