Related Experiment Video
Updated: Nov 30, 2025

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
Published on: May 9, 2014
FMEA occurrence values for four failure modes occurring using look-up tables for dose calculations
Geoff Nelson1, Adam Paxton1, Jeremy Kunz1
1Department of Radiation Oncology, University of Utah, Salt Lake City, UT, USA.
Purpose:
For a number of different treatment types [such as Total Body Irradiation (TBI), etc.] most institutions utilize tables from commissioned databooks to perform the dose calculations. Each time one manually looks up data from a large table and then copies the numbers for a manual calculation, there is potential for errors. While a second check effectively mitigates the potential error from such calculations, information regarding the frequency and nature of such mistakes is important to develop protocols and workflows that avoid related errors.
Methods:
Five years' worth of TBI calculations were reviewed. Each calculation was re-performed and evaluated against the original calculation and original second check. Any discrepancies were noted and those discrepancies were checked to see if the number was the result of misreading from the look-up table, a typo, copying/skipping partially redundant steps, or rounding/avoiding interpolation. The number of calculations that contained these various types of discrepancies was tallied and percentages representing the frequency of said discrepancies were derived.
Results:
All of the discrepancies only resulted in a monitor unit (MU) calculation difference of <1.7%. Typos, looking up wrong values from tables, rounding/avoiding interpolation, and skipping steps occurred in 10.4% ( 3.1%), 6.3% ( 2.5%), 53.1% ( 5.1%), and 4.2% ( 2.0%) of MU calculations, respectively.
Conclusions:
While all of the discrepancies only resulted in a monitor unit (MU) calculation difference of <1.7%, this review shows how frequently various discrepancies can occur. Typos and rounding/avoiding interpolation are the steps most likely to potentially cause a miscalculation of MU. To avoid direct human interaction on such a large repetitive scale, creating forms that calculate MU automatically from initial measurement data would reduce the incidences that numbers are written/transcribed and eliminate the need to look up data in a table, thus reducing the chance for error.
More Related Videos
Related Concept Videos
Fatigue
Hazard Rate
Biological Effects of Radiation
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Dose Size and Dosing Frequency: Determination Methods
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses

