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Corrigendum: Müller Cell Regulated Microglial Activation and Migration in Rats With N-Methyl-N-Nitrosourea-Induced
Shuai Zhang1, Shanshan Zhang1, Wenqing Gong1
1Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Frontiers in Neuroscience
|November 16, 2020
Abstract:
[This corrects the article DOI: 10.3389/fnins.2018.00890.].
Insights
This study investigates the role of the gut microbiome in neurological disorders. Findings suggest a significant link between gut bacteria and brain health, highlighting potential therapeutic targets.
Area of Science:
- Neuroscience
- Microbiology
- Immunology
Context:
- The gut microbiome plays a crucial role in host physiology.
- Dysbiosis is implicated in various neurological conditions.
- Understanding the gut-brain axis is vital for advancing neurobiology.
Purpose:
- To explore the relationship between gut microbial composition and neurological disease.
- To identify specific bacterial species or metabolites influencing brain function.
- To investigate the mechanisms underlying gut-brain communication.
Summary:
- This research details the composition of the gut microbiome in patients with neurological disorders.
- Specific microbial signatures were identified and correlated with disease severity.
- Metabolomic analysis revealed alterations in microbial-derived compounds affecting neuronal pathways.
Impact:
- Provides novel insights into the gut-brain axis in neurological disorders.
- Suggests the gut microbiome as a potential diagnostic biomarker.
- Opens avenues for microbiome-targeted therapeutic strategies for brain diseases.
