Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypersensitivity reactions from antineoplastic agents.

R B Weiss1, J R Baker

  • 1Section of Medical Oncology, Walter Reed Army Medical Center, Washington, DC.

Cancer Metastasis Reviews
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An efficient synthesis of epoxydiynes and a key fragment of neocarzinostatin chromophore.

Organic letters·2006
Same author

Acute and chronic gas bubble lesions in cetaceans stranded in the United Kingdom.

Veterinary pathology·2005
Same author

Stress management. Stress, like pain, is inevitable--suffering is optional.

The Journal of the Arkansas Medical Society·2005
Same author

Central neuropeptide B administration activates stress hormone secretion and stimulates feeding in male rats.

Journal of neuroendocrinology·2004
Same author

Deformability of poly(amidoamine) dendrimers.

The European physical journal. E, Soft matter·2004
Same author

Diagnostic delays of adult patients admitted to hospital with diabetic ketoacidosis.

Diabetic medicine : a journal of the British Diabetic Association·2004
Same journal

HER2 assessment in urothelial carcinoma: standardization challenges and the path forward.

Cancer metastasis reviews·2026
Same journal

Resolving translational challenges in cancer biology through yeast experimental evolution.

Cancer metastasis reviews·2026
Same journal

Spheroids and organoids to study long noncoding RNAs in cancer: how they could replace animal models.

Cancer metastasis reviews·2026
Same journal

Strategies and successes of smoking cessation methods in head and neck cancer patients: a systematic review.

Cancer metastasis reviews·2026
Same journal

The Hippo signaling pathway in pediatric brain tumors: molecular mechanisms and therapeutic opportunities.

Cancer metastasis reviews·2026
Same journal

Antibody-drug conjugates in breast cancer brain and leptomeningeal metastases: mechanistic insights and therapeutic progress.

Cancer metastasis reviews·2026
See all related articles

Antitumor drugs can cause hypersensitivity reactions, impacting cancer treatment. This review details assessing these reactions to ensure correct drug attribution and patient management.

Area of Science:

  • Oncology
  • Immunology
  • Pharmacology

Background:

  • Antitumor drugs can trigger hypersensitivity reactions, complicating cancer therapy.
  • Some agents, like L-asparaginase and taxol, frequently cause reactions, hindering repeated administration.
  • Hypersensitivity reactions to antineoplastic agents span Gell and Coombs types I, II, III, and IV.

Purpose of the Study:

  • To review current knowledge on hypersensitivity reactions to antineoplastic drugs.
  • To provide a systematic approach for evaluating these reactions in cancer patients.

Main Methods:

  • Literature review of hypersensitivity reactions to antineoplastic agents.
  • Discussion of diagnostic approaches to identify the causative agent and mechanism.

Related Experiment Videos

Main Results:

  • Most hypersensitivity reactions to antitumor drugs are Type I, but other types occur.
  • Mechanisms underlying these reactions are often not well-elucidated.
  • Distinguishing drug-induced reactions from those caused by ancillary products is crucial.

Conclusions:

  • Hypersensitivity reactions are a significant concern with antitumor drugs.
  • Systematic assessment is necessary to confirm the offending agent and understand the reaction mechanism.
  • Proper evaluation aids in managing and potentially continuing essential cancer treatments.