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Oxidative Stress From Exposure to the Underground Space Environment
Hongbiao Yu1,2, Yijie Gao1, Rong Zhou1
1Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University) of Ministry of Education, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Frontiers in Public Health
|November 16, 2020
Summary
Living in underground spaces causes oxidative stress due to hypoxia, toxic particles, and low radiation. More research is needed to understand health effects and develop protective measures.
Area of Science:
- Environmental Health
- Toxicology
- Biomedical Sciences
Background:
- Increasing human presence in underground spaces necessitates understanding environmental health impacts.
- Unique underground conditions like hypoxia, toxic particles, and low radiation pose potential health risks.
- Current knowledge on the biological effects of underground environments is limited.
Purpose of the Study:
- To review the effects of underground environmental factors on living organisms, focusing on oxidative stress.
- To highlight the need for further research into pathophysiological mechanisms and protective strategies.
Main Methods:
- Literature review of studies examining oxidative stress markers in organisms exposed to underground environments.
- Analysis of effects related to hypoxia, toxic atmospheric particles, and low background radiation.
Main Results:
- Organisms in underground environments show significant oxidative stress.
- Observed effects include altered oxidant levels, changes in antioxidant enzyme activity, and genetic damage.
- These changes can potentially lead to disease states.
Conclusions:
- Underground environments induce oxidative stress in living organisms.
- Further research is crucial to fully elucidate mechanisms and explore protective measures for humans and other organisms.
- Understanding these biological effects is essential for ensuring health and safety in subterranean settings.
Keywords:
environmenthypoxiclow background radiationorganismoxidative stresstoxic particlesunderground spaceMore Related Videos
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