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Do corticosteroids reduce postoperative pain following third molar intervention?
Chollathit Sugragan1, Nattapong Sirintawat1, Sirichai Kiattavornchareon1
1Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Journal of Dental Anesthesia and Pain Medicine
|November 16, 2020
Summary
Corticosteroids, like methylprednisolone and dexamethasone, effectively reduce pain after wisdom teeth surgery when given via intramuscular injection. The best results are achieved when administered before the procedure.
Area of Science:
- Oral Surgery
- Pharmacology
- Evidence-Based Dentistry
Background:
- Corticosteroids are commonly used by oral surgeons to manage swelling after wisdom teeth removal.
- Evidence supporting their efficacy in pain reduction following this procedure remains limited.
Purpose of the Study:
- To systematically review existing literature on the effectiveness of corticosteroids for pain reduction after wisdom teeth surgery.
Main Methods:
- A systematic search of Science Direct, PubMed, and MEDLINE databases was conducted.
- Randomized controlled trials published between 1998 and 2017 were included, following a Patient Intervention Comparison Outcome (PICO) strategy.
Main Results:
- Twenty-seven articles comprising 36 comparative cases were analyzed.
- Methylprednisolone and dexamethasone were the most frequently used corticosteroids.
- Intramuscular corticosteroid injections demonstrated optimal pain reduction irrespective of administration timing.
Conclusions:
- Corticosteroids serve as an effective adjuvant therapy for managing pain post-wisdom teeth surgery.
- Intramuscular administration of methylprednisolone or dexamethasone is the preferred method for pain relief.
- Preoperative administration of corticosteroids is considered ideal for maximizing pain reduction benefits.
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