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Updated: Nov 30, 2025

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy
Published on: January 31, 2025
Thromboelastometry-guided neuraxial anesthesia in a parturient with severe thrombocytopenia due to large granular
Chloe Getrajdman1, Matthew Sison1, Colleen Yen1
1Department of Anesthesiology, Perioperative and Pain Medicine.
Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.
Severe thrombocytopenia (platelet count <50 000/μl) in pregnancy is uncommon and is generally considered a contraindication to neuraxial anesthesia. We present a case of a parturient who presented with severe thrombocytopenia secondary to bone marrow failure. After receiving platelet and cryoprecipitate transfusions to correct coagulopathy as verified by thromboelastometry, neuraxial anesthesia was safely utilized.
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