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Related Concept Videos

Three-Dimensional Analysis of Strain01:29

Three-Dimensional Analysis of Strain

458
Three-dimensional strain analysis is crucial for understanding how materials deform under stress, particularly in elastic, homogeneous materials. This method employs principal stress axes to simplify complex stress states into more understandable forms. Subjected to stress, a small cubic element within a material either expands or contracts along these axes, transforming into a rectangular parallelepiped. This transformation effectively illustrates the material's deformation. The principal...
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Measurements of Strain01:27

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Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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True Stress and True Strain01:28

True Stress and True Strain

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Engineering stress is calculated as the load divided by the original, undeformed cross-sectional area. It approximates a material under load. This approximation is especially relevant post-yield in ductile materials. Though engineering stress-strain diagrams are often used for their convenience and accessibility, they can sometimes fall short in accuracy, particularly when dealing with large strain values.
In contrast, true stress offers a more precise portrayal. It is computed by dividing the...
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Related Experiment Video

Updated: Nov 30, 2025

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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CardIAc: an open-source application for myocardial strain analysis.

Ariel Hernán Curiale1,2, Agustín Bernardo3,4, Rodrigo Cárdenas5,3

  • 1Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. ariel.curiale@cab.cnea.gov.ar.

International Journal of Computer Assisted Radiology and Surgery
|November 16, 2020
PubMed
Summary
This summary is machine-generated.

CardIAc is a new open-source software for quantifying left ventricle myocardial strain from cardiac MRI. It offers adaptable motion tracking for improved accuracy in research settings.

Keywords:
3D Slicer extensionCardiac quantificationOpen sourceStrainStrain rate

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Area of Science:

  • Cardiovascular Imaging
  • Medical Software Development
  • Biomedical Engineering

Background:

  • Accurate quantification of left ventricle myocardial strain is crucial for diagnosing and monitoring cardiovascular diseases.
  • Commercial software for strain analysis can be expensive and lack flexibility for specific research needs.

Purpose of the Study:

  • To introduce CardIAc, an open-source application for myocardial strain quantification in cardiac MRI.
  • To provide a flexible platform for researchers to adapt motion tracking strategies for improved strain accuracy.

Main Methods:

  • CardIAc was developed as a 3D Slicer extension for ease of installation and use.
  • The workflow includes data loading, 3D heart modeling, strain analysis, and visualization.
  • The software is designed for users with programming skills to modify and customize its performance.

Main Results:

  • Evaluation on a public dataset (STACOM 2011) showed a median error of 3.66 mm for myocardial motion estimation.
  • Global strain curves correlated well with existing literature for healthy patients.
  • Mean global errors on a synthetic dataset were 4.07% (circumferential), 7.76% (radial), and 8.18% (longitudinal).

Conclusions:

  • CardIAc is a novel open-source application for myocardial strain analysis, distributed under a BSD license.
  • The results demonstrate the application's capability and potential for research in cardiovascular imaging.