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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Parenting stress during infancy is a risk factor for mental health problems in 3-year-old children
Nayantara Hattangadi1, Katherine T Cost1, Catherine S Birken2,3,4,5,6
1Department of Psychiatry, Hospital for Sick Children, Toronto, ON, Canada.
Insights
Parenting stress in infancy was linked to a doubled risk of mental health issues in 3-year-old children. This study highlights the importance of early parental well-being for child development.
Area of Science:
- Child Psychology
- Developmental Pediatrics
- Parental Mental Health
Background:
- The relationship between parent and child mental health is increasingly studied.
- The specific impact of early parenting stress on preschooler mental health requires further investigation.
Purpose of the Study:
- To assess the association between parenting stress experienced during infancy and the presence of mental health problems in 3-year-old children.
Main Methods:
- A prospective cohort study involved healthy preschool-aged children from primary care practices in Toronto.
- Parenting stress was measured using the Parent Stress Index Short Form (PSI-SF) in infancy (0-16 months).
- Child mental health was assessed at 3-4 years using the preschool Strengths and Difficulties Questionnaire (TDS), with statistical analysis including hierarchical linear and logistic regression.
Main Results:
- Parenting stress during infancy significantly correlated with mental health problems in 3-year-old children (β = 0.35, p < 0.001).
- Elevated parenting stress was associated with a 2.26 times higher odds of reporting higher total difficulties scores (OR = 2.26, p < 0.01).
Conclusions:
- Infancy parenting stress is a significant predictor of mental health problems in early childhood.
- Children whose parents reported stress during infancy demonstrated approximately double the odds of experiencing mental health challenges by age 3.
Background:
Although research on the relationship between parent and child mental health is growing, the impact of early parenting stress on preschool-aged children's mental health remains unclear. The objective was to evaluate the association between parenting stress during infancy and mental health problems in 3-year-old children.
Methods:
A prospective cohort study of healthy preschool-aged children recruited from 9 primary care practices in Toronto, Canada was conducted through the TARGet Kids! primary care practice-based research network. Parenting stress was measured when children were between 0 to 16 months of age, using the Parent Stress Index Short Form, PSI-SF. Parent-reported child mental health problems were measured at 36 to 47 months using the preschool Strengths and Difficulties Questionnaire, total difficulties score (TDS). Hierarchical linear regression analysis was used to investigate the association between standardized PSI-SF and TDS, adjusted for child age, sex, temperament, sleep duration and household income. To strengthen clinical interpretation, analysis was repeated using adjusted multivariable logistic regression (TDS dichotomized at top 20%).
Results:
A total of 148 children (mean ± SD age, 37.2 ± 1.7 months, 49% male) were included in the analysis. Parenting stress during infancy (11.4 ± 3.1 months of age) was significantly associated with mental health problems in 3-year-old children (β = 0.35; 95% CI = 0.20-0.49, p < 0.001). Higher parenting stress was also associated with increased odds of higher TDS (OR = 2.26, 95% CI = 1.69-2.83, p < 0.01).
Conclusion:
Healthy preschool-aged children with parents reporting parenting stress during infancy had a 2 times higher odds of mental health problems at 3 years.
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