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Depression, Anxiety, and Acute Stress Disorder Among Patients Hospitalized With COVID-19: A Prospective Cohort Study

Catherine Parker1, Daniel Shalev2, Ian Hsu2

  • 1Columbia University Vagelos College of Physicians and Surgeons, New York, NY.

Journal of the Academy of Consultation-Liaison Psychiatry
|November 17, 2020
PubMed

Insights

Hospitalized coronavirus disease 2019 patients frequently experienced anxiety and depression. While anxiety symptoms improved post-discharge, depression persisted, and some patients developed acute stress disorder.

Area of Science:

  • Psychiatry
  • Infectious Diseases
  • Public Health

Background:

  • The psychiatric impact of coronavirus disease 2019 (COVID-19) on hospitalized patients is not well understood.
  • Limited data exists on the prevalence and trajectory of mental health conditions following COVID-19 hospitalization.

Purpose of the Study:

  • To determine the prevalence of anxiety, depression, and acute stress disorder in adult patients hospitalized with COVID-19.
  • To assess the changes in these psychiatric symptoms at a 2-week follow-up after hospital discharge.

Main Methods:

  • Adult patients admitted to medical wards for COVID-19 were enrolled.
  • Initial screening for depression, anxiety, and delirium was performed.
  • Patients were followed up via phone at 2 weeks for rescreening of depression, anxiety, and acute stress disorder symptoms.

Main Results:

  • Of 58 enrolled subjects, 44 completed the study.
  • Initially, 36% reported anxiety and 29% reported depression.
  • At follow-up, 9% had anxiety, 20% had depression, and 25% had acute stress disorder symptoms.

Conclusions:

  • A substantial proportion of COVID-19 inpatients exhibit symptoms of depression and anxiety.
  • Anxiety symptoms generally improved, but depression remained persistent.
  • A notable minority developed acute stress disorder, mostly mild to moderate in severity.
Abstract

Keywords:
anxietydepressionepidemiologymental healthpost traumatic stress

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