Related Experiment Video
Updated: Nov 30, 2025

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
A review on how to do hematology consults during COVID-19 pandemic
1Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA 01608, USA.
Insights
The COVID-19 pandemic significantly impacts the blood system, presenting unique hematological findings with prognostic value. Hematologists face challenges managing these complications with evolving, interim guidelines.
Area of Science:
- Hematology
- Infectious Diseases
- Internal Medicine
Background:
- The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic presents unique hematological findings.
- These findings have prognostic implications and differ from other viral infections.
- Managing hematological complications in critically ill COVID-19 patients is challenging due to the disease's novelty.
Purpose of the Study:
- To provide background context on the impact of COVID-19 on the blood system.
- To summarize current interim guidelines for managing COVID-19-associated hematological issues.
Main Methods:
- Literature review of COVID-19's hematological manifestations.
- Analysis of interim guidelines from major hematology societies.
- Synthesis of clinical observations and prognostic indicators.
Main Results:
- COVID-19 exhibits distinct hematological alterations, including changes in blood cell counts and coagulation parameters.
- These hematological changes correlate with disease severity and patient outcomes.
- Interim guidelines offer a framework for managing hematological complications, emphasizing case-by-case tailoring.
Conclusions:
- Hematologists play a crucial role in managing COVID-19 patients.
- Understanding unique hematological findings is key to prognosis and treatment.
- Adaptable management strategies are essential given the evolving nature of COVID-19 and its hematological impact.
Abstract:
The ongoing COVID-19 pandemic is the most trending and talked topic across the World. From its point of origin in Wuhan, China to clinical laboratory at NIH, a mere six-month-old SARS-CoV-2 virus is keeping the clinicians, and scientists busy at various fronts. However, COVID-19 is an emerging and evolving disease and each day brings in more data, new figures, and findings from the field of clinical practice. The role of hematologists has been increasingly recognized during the current pandemic because of several reasons. Most important of them are the characteristic hematological findings of COVID-19 patients that also have prognostic implications and that were not seen in other viral infections. The treatment of hematological complications in COVID-19 patients is very challenging given the critical care setting. There are interim and limited guidelines thus far due to the novelty of the disease. As this remains to be a quite fluid situation, all the appropriate medical societies including the major hematology bodies are proposing initial and interim guidelines (e.g. ASH guideline). This puts a hematologist on consult service in a dubious position where, he/she must tailor the recommendations on case to case basis. The purpose of this review is to provide the background context about the impact of COVID-19 on the blood system and to summarize the current interim guidelines to manage the associated hematological issues in COVID-19 infection.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Regulation of Hematopoietic Stem Cells
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hemodialysis II: Procedure and Complications

