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COVID-19 outcomes in UK centre within highest health and wealth band: a prospective cohort study

Gie Ken-Dror1, Charles Wade2, Shyam Sharma3

  • 1Institute of Cardiovascular Research, Royal Holloway University of London, Egham, UK.

BMJ Open
|November 17, 2020
PubMed

Insights

This study analyzed COVID-19 patient outcomes in an affluent UK region, finding that advanced age, male gender, and comorbidities like cardiac disease, diabetes, and dementia were linked to adverse outcomes, similar to other regions.

Area of Science:

  • Medical Research
  • Epidemiology
  • Public Health

Background:

  • Previous studies suggested worse COVID-19 outcomes in deprived regions.
  • Understanding COVID-19 patient characteristics and outcomes is crucial for healthcare planning.

Purpose of the Study:

  • To describe the characteristics and outcomes of hospitalized patients with COVID-19 in an affluent region of the UK.
  • To identify risk factors associated with adverse outcomes in this population.

Main Methods:

  • Prospective cohort study involving 429 adult inpatients with laboratory-confirmed COVID-19.
  • Data collected included demographics, comorbidities, intensive care unit (ICU) admission, and mortality.
  • Statistical analysis identified factors associated with adverse outcomes.

Main Results:

  • The study included 429 adult inpatients (mean age 70±18 years; 56.4% male).
  • 19.1% required ICU admission and 31.9% died.
  • Adverse outcomes were associated with older age, male gender, cardiac disease, diabetes mellitus, and dementia. Ethnicity and BMI did not significantly impact outcomes.

Conclusions:

  • This study demonstrates that COVID-19 complication and mortality rates in an affluent region are similar to those reported in more deprived areas.
  • The findings highlight the importance of considering age and comorbidities in managing COVID-19 patients, regardless of socioeconomic status.
Abstract

Keywords:
COVID-19epidemiologypublic health

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