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Large vessel thrombosis in patient with COVID-19, a case series

Aram Baram1, Fahmi H Kakamad1,2,3, Hadi M Abdullah4

  • 1College of Medicine, University of Sulaimani, Sulaimani, Kurdistan, Iraq.

Annals of Medicine and Surgery (2012)
|November 17, 2020
PubMed

Insights

Coronavirus disease-19 (COVID-19) is a significant risk factor for large vessel thrombosis (LVT), potentially leading to severe outcomes. Vigilance and prompt surgical consultation are crucial for managing COVID-19 patients at risk of LVT.

Area of Science:

  • Vascular Medicine
  • Infectious Diseases
  • Cardiology

Background:

  • Large vessel thrombosis (LVT) is an underreported complication of Coronavirus disease-19 (COVID-19).
  • Understanding the implications of LVT in COVID-19 is critical due to its potential severity.

Purpose of the Study:

  • To present a case series of patients with Coronavirus disease-19 (COVID-19) and documented large vessel thrombosis (LVT).
  • To highlight the association between COVID-19 and LVT.

Main Methods:

  • A multicenter prospective case series involving consecutive patients diagnosed with COVID-19 and LVT.
  • Large vessels were defined as those equal to or larger than the popliteal artery.
  • Follow-up duration averaged 4 months.

Main Results:

  • The study included 22 patients (86.4% male, mean age 48.4 years).
  • Pulmonary embolism was confirmed in 18.2% of cases via CT scan.
  • All patients exhibited ground glass opacities on chest CT and elevated D-Dimer levels (mean 3601 ng/ml).

Conclusions:

  • Coronavirus disease-19 (COVID-19) presents a hidden risk for developing large vessel thrombosis (LVT), which can be life-threatening and necessitate major amputation.
  • Even with anticoagulant therapy, COVID-19 patients remain susceptible to LVT.
  • A high index of suspicion and early surgical consultation are recommended for COVID-19 patients with suspected LVT.
Abstract

Keywords:
COVID-19IschemiaSARS-CoV-2Thrombosis

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