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Anticoagulation in COVID - 19: An Update.
Nishant R Tiwari1, Khalid I Khatib2, Subhal B Dixit3
1Byramjee Jeejeebhoy Medical College and Sassoon General Hospital, Pune, Maharashtra, India.
Summary
COVID-19 (severe acute respiratory syndrome-corona virus-2) infection is linked to blood clotting issues. Understanding and managing these thrombotic events is crucial for patient outcomes.
Area of Science:
- Infectious Diseases
- Hematology
- Critical Care Medicine
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, presents significant challenges in patient management.
- SARS-CoV-2 infection is associated with abnormal coagulation parameters and a higher risk of thrombotic events.
- Deranged coagulation markers like D-dimers can predict disease severity and prognosis.
Purpose of the Study:
- To explore the occurrence, prevention, and management of thrombotic events in COVID-19 patients.
- To highlight the importance of addressing venous thromboembolism (VTE) in the context of COVID-19.
- To provide insights into the relationship between COVID-19 and thrombotic complications.
Main Methods:
- Review of current literature on COVID-19 and thrombotic events.
- Analysis of coagulation parameters in COVID-19 patients.
- Discussion of prophylactic and therapeutic strategies for VTE prevention and management.
Main Results:
- COVID-19 significantly impacts coagulation, increasing thrombotic risk.
- Specific coagulation markers correlate with disease severity and prognosis.
- Prophylactic anticoagulation and mechanical devices are key in VTE prevention.
Conclusions:
- Effective prevention and management of thrombotic events are vital for reducing morbidity and mortality in COVID-19.
- Further research is needed to optimize therapies for COVID-19-associated thrombosis.
- A focused approach to VTE can mitigate the burden of thrombotic diseases in this pandemic.
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