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Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

Jaspreet K Osan1,2, Sattya N Talukdar1,2, Friederike Feldmann3

  • 1Department of Biomedical Sciences, University of North Dakota School of Medicine & Health Sciences, Grand Forks, ND 58202, USA.

Biorxiv : the Preprint Server for Biology
|November 17, 2020
PubMed
Summary

SARS-CoV-2 infects airway goblet cells, which are crucial for viral replication, especially in Chronic Obstructive Pulmonary Disease (COPD) patients. This study identifies goblet cells as a novel target for COVID-19 infection and potential therapeutic strategies.

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