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Phytotoxic Neocassane Diterpenes from Eragrostis plana
Ana Paula P Klein Hendges1, Elaine Fernanda Dos Santos1, Sirlei D Teixeira
1Department of Chemistry, Federal University of Parana, Avenida Cel. Francisco H. dos Santos 100, Jardim das Americas, Curitiba PR 81530-900, Brazil.
Abstract:
Five new neocassane-like diterpenes (1-5) were isolated from the roots of Eragrostis plana. Their structures were elucidated by spectroscopic data, and the absolute configurations of the representative compounds neocassa-12(17),15-dien-3-one (2) and neocassa-12(13),15-diene-3,14-dione (5) were assigned by vibrational circular dichroism. The phytotoxic activity of compounds 3, 4, and 5 was evaluated against the germination and growth of Ipomoea grandifolia and Euphorbia heterophylla. Compound 4 exhibited the most potent activity for growth variables, resulting in the smallest radicle length of I. grandifolia and in the smallest aerial part length of E. heterophylla. Compound 5 reduced the germination speed index more effectively than the herbicide glyphosate (Roundup).
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