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Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
Is the Frequency of Candidemia Increasing in COVID-19 Patients Receiving Corticosteroids?
Cezar V W Riche1,2, Renato Cassol3, Alessandro C Pasqualotto2,4
1Hospital Ernesto Dornelles, Porto Alegre 90160-092, Brazil.
Abstract:
Corticosteroids have potent anti-inflammatory and immunosuppressive effects. Recently, these medications have gained importance in the treatment of severe COVID-19. Here we present data demonstrating a marked (10-fold) increase in frequency of candidemia in hospitalized patients with COVID-19 receiving corticosteroids in Brazil. Overall mortality was 72.7%, despite antifungal therapy. Physicians should be aware of the potential risk for candidemia among severely ill COVID-19 patients receiving high-doses of corticosteroids.
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