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Pulmonary "cyclosporinoma" mimicking infection after heart transplantation
1Department of Cardiothoracic Surgery, University of Newcastle upon Tyne, England.
The Journal of Heart Transplantation
|November 1, 1987
Abstract:
Tissue from a transthoracic needle biopsy, which was performed as part of the investigation of an undiagnosed left upper lobe opacity in a patient after orthotopic heart transplantation, revealed numerous macrophages loaded with oil globules. No causative organisms were present. High-pressure liquid chromatography showed a similar profile to the oil in which cyclosporine is suspended. The lesion appears to have been caused by aspiration of cyclosporine.