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Updated: Nov 29, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
[Unexpected deposits in the upper gastrointestinal tract : When medical history matters]
C Wagener1, S Schindera2, T Kuntzen3
1Institut für Pathologie, Kantonsspital Aarau, Aarau, Schweiz. carolin.wagener@ksa.ch.
Abstract:
In order to regulate their phosphate uptake, patients with end-stage renal disease rely on phosphate binders such as lanthanum carbonate (LC). The earliest histopathological reports of this rare entity in the gastrointestinal mucosa were described and published in 2015.We present a case of an 80-year-old patient with LC gastro-enteropathy. Histopathologically it can mimic other drug-induced depositions and even infectious or neoplastic entities. Evaluation of the patient's medical and especially drug history is essential to obtain the appropriate diagnosis. We present an overview of the clinical presentation and histological differential diagnosis of LC.
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