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Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
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Activation of Aptamers with Gain of Function by Small-Molecule-Clipping of Intramolecular Motifs

Mengjiao Huang1, Tingyu Li1, Yuanfeng Xu1

  • 1The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, 361005, China.

Angewandte Chemie (International Ed. in English)
|November 18, 2020
PubMed

Keywords:
aptamersgain of functionnucleic acidsregulation of binding affinityselection

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