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Successfully minimal approach ViV-TAVR without angiography in a severe restenosis with renal dysfunction 17 years
Xiaofei Jiang1, Zhe Zhang1, Kun Wang1
1Cardiology Department, Zhuhai People's Hospital, (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, Guangdong, P. R. China.
Insights
Transcatheter aortic valve replacement (TAVR) can be performed without angiography in patients with recurrent aortic stenosis and kidney dysfunction. This angiography-free TAVR approach may improve outcomes for high-risk patients.
Area of Science:
- Cardiovascular Interventional Therapy
- Nephrology
- Geriatric Medicine
Background:
- Severe aortic stenosis (AS) is a significant cause of death in elderly individuals.
- Transcatheter aortic valve replacement (TAVR) is a key treatment, but often involves patients with advanced heart failure and chronic kidney disease.
- Pre-procedural imaging like CT and angiography is standard for TAVR but can worsen kidney function.
Observation:
- A patient with severe recurrent AS after prior surgical aortic valve replacement (SAVR) and worsening renal dysfunction was considered for TAVR.
- Standard angiography was contraindicated due to renal impairment.
- Valve-in-valve (ViV) TAVR was successfully performed using pre-procedural evaluation without angiography.
Findings:
- The angiography-free ViV TAVR successfully treated the restenosis.
- The patient's renal function did not deteriorate post-procedure.
- This approach avoided contrast-induced acute kidney injury (CI-AKI).
Implications:
- Angiography-free TAVR is a viable and potentially safer option for patients with aortic restenosis and renal dysfunction.
- This strategy may expand TAVR eligibility for high-risk populations.
- Minimizing contrast exposure is crucial for patients with compromised kidney function undergoing TAVR.
Abstract:
Severe aortic stenosis (AS) is a major cause of morbidity and mortality in the elderly. Transcatheter aortic valve replacement (TAVR) is an approach in cardiovascular interventional therapy. As we known, most of the candidates for TAVR are suffered from advanced heart dysfunction (New York Heart Association functional class III or IV) and chronic kidney disease. However, contrast-enhanced computed tomography and coronary angiography are necessary for pre-procedures for TAVR. TAVR could have adverse effects on kidney function including contrast-induced acute kidney injury (CI-AKI), which is related to poor prognosis. In a severe recurrent valve stenosis with progressive renal dysfunction, receiving surgical aortic valve replacement (SAVR) using bioprosthetic valve (BV) 17 years ago, we successfully reversed restenosis by performing pre-procedure evaluating and valve-in-valve (ViV) TAVR without angiography. Angiography-free TAVR may be a beneficial approach for patients with aortic restenosis after SAVR complicated with renal dysfunction.
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