Early pseudophakic keratopathy: revealing macrophage reaction in endothelial layer

The pathology of early pseudophakic keratopathy is demonstrated in a corneal button obtained at penetrating keratoplasty for persisting corneal edema and bullous keratopathy 4 months following extracapsular cataract extraction with a posterior chamber lens implant. Histological examination revealed a distinct cell loss and a macrophage reaction that was centered on degenerating endothelial cells in the corneal endothelium.