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Updated: Nov 29, 2025

A Murine Tail Lymphedema Model
Published on: February 10, 2021
Lymphedema resulting from filariasis successfully treated by surgery
Karlina Novianti K1, Siswanto Wahab1, Khairuddin Djawad1
1Department of Dermatology and Venereology.
Abstract:
Filariasis is an infectious disease caused by a filarial worm infection transmitted by mosquito bites. The disease can result in reduced work productivity, disability and social stigma. This disease transmission process begins when a mosquito bite and suck the blood containing the microfilaria. Filarial infections have been grouped into three categories based on their location diseases of the disease: (1) lymphatics, (2) skin, and (3) body cavities. Morbidity is almost entirely due to the species that cause lymphatic diseases, and skin diseases to a lesser degree. A 28-year-old male came with a chief complaint of swollen right leg since four years ago which worsened in the last three months. Upon physical examination, edema, fibrosis, and hyper-pigmented plaques were present on the right lower extremity. The blood microfilariae examination was positive for Wuchereria bancrofti. The lymphedema did not resolve despite of antifilarial treatment and surgery was eventually performed to resect the fibrous tissue and subcutaneous edema. The patient responded well to the treatment with a significant reduction in the edema. No complication was present until two years after surgery.
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