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Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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Light control of RTK activity: from technology development to translational research

Anna V Leopold1, Vladislav V Verkhusha1,2

  • 1Medicum , Faculty of Medicine , University of Helsinki , Helsinki 00290 , Finland.

Chemical Science
|November 19, 2020
PubMed
Summary

Optogenetic and optochemical technologies use light to control receptor tyrosine kinases (RTKs) for cancer, diabetes, and neurodegeneration therapies. These light-based methods offer precise, non-invasive control over RTK signaling, overcoming limitations of conventional treatments.

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