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Group A beta-hemolytic streptococcal bacteremia in children
1Department of Pediatrics B, Soroka University Hospital, Beer-Sheva, Israel.
The Pediatric Infectious Disease Journal
|November 1, 1987
Summary
Group A beta-hemolytic streptococcal bacteremia in children is often linked to skin infections, particularly in winter. Healthy infants had better outcomes than older children with underlying conditions.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Group A beta-hemolytic Streptococcus (GABHS) is a significant pathogen in pediatric infections.
- Bacteremia, the presence of bacteria in the bloodstream, can lead to severe complications.
Purpose of the Study:
- To report on cases of GABHS bacteremia in children.
- To identify risk factors and outcomes associated with GABHS bacteremia.
Main Methods:
- Retrospective case series analysis.
- Review of 20 pediatric cases diagnosed between 1980 and 1987.
- Clinical data including patient demographics, sources of infection, complications, and outcomes were analyzed.
Main Results:
- Most cases (20) occurred in winter, with skin and soft tissues being the most common sources.
- Two distinct patient groups emerged: 12 healthy infants with favorable outcomes and 8 older children with malnutrition and comorbidities who experienced more focal infections (pneumonia, meningitis, arthritis/osteomyelitis) and worse prognosis.
- Three patients died.
Conclusions:
- Pediatric GABHS bacteremia presents differently based on host factors, with significant morbidity and mortality in vulnerable children.
- Early identification and management are crucial, especially in children with underlying health issues.